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The content of this article or section is canon
- It contains Star Trek canon referenced in the game or its lore. However, it does not directly appear in Star Trek Online. Broader Star Trek lore can be looked up on Memory Alpha and Memory Beta.

The Daystrom Institute is a Federation research and development organization established in the 23rd cenutry. It is affiliated to another organization known as the Soong Foundation.

In 2380 the institute predicted that the Cardassian Union could fall in as little as three years without more successful projects such as the Andak project.

Seven of Nine joined the Institute in 2385 after she quit Starfleet in protest at the dismantling of the its Borg taskforce.

The Jellyfish, a craft designed for the institute by Geordi La Forge, is successfuly launched in 2387. It is equipped with trans-metaphasic shielding designed to withstand conditions that would destroy most other ships. It is subsequently used by Spock to counter the Hobus supernova.

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Starfleet
Faction Federation
Details StarfleetUnited Federation of Planets • Human • Vulcan • Andorian • TellariteEarth • Earth Space Dock • Starfleet Academy • Vulcan (planet) • Andoria • Bajor • Deep Space 9
Ground Forces Ensign Security Officer • Ensign Engineering Officer • Ensign Medic • Lieutenant Tactical Officer • Engineer (Mob) • Combat Medic (Mob) • Commander Tactical Officer • Commander Engineering Officer • Commander Science Officer • Security Chief • Chief Engineer (Mob) • Chief Medical Officer (Mob)
Starships Federation Shuttlecraft (Mob) • Peregrine Fighter (Mob) • Federation Frigate • Federation Cruiser (Mob) • Federation Escort (Mob) • Federation Science Vessel (Mob) • Galaxy Class Cruiser • Rhode Island Science Vessel • Intrepid Class Science Vessel • Nebula Class Science Vessel • Typhoon Class Battleship • Armitage Class Escort Carrier • Prometheus Class Escort • Multi-Mission Explorer (Mob) • Federation Battlecruiser • Chimera Class Heavy Destroyer • Jupiter Class Dreadnought • Galaxy Dreadnought Cruiser • Odyssey Dreadnought Cruiser
NPCs Julian Bashir • Ethan Burgess • Richard Castillo • The Doctor • D'Vak • Franklin Drake • Elisa Flores • Harry Kim • Kira Nerys • James Kurland • Leonard McCoy • Nog • Aennik Okeg • Miral Paris • Tom Paris • Jorel Quinn • Chal Rexx • Va'Kel Shon • Spock • Masc Taggart • Tuvok • T'nae • Grigori Yanishev • Natasha Yar
NPC starships U.S.S. Aventine • U.S.S. Belfast • U.S.S. Chimera • U.S.S. Challenger • U.S.S. Defiant • U.S.S. de Witt • U.S.S. Enterprise (NCC-1701) • U.S.S. Enterprise (NCC-1701-C) • U.S.S. Enterprise-F • U.S.S. Hofmann • U.S.S. Houston • U.S.S. Khitomer • U.S.S. Kirk • U.S.S. Musashi • U.S.S. Rhode Island • U.S.S. Sally Ride • U.S.S. Voyager
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