The U.S.S. Houston is an Odyssey-class Dreadnought active in 2410.
- “Hive Onslaught”: The Houston, commanded by Admiral D'Vak, leads the players in an assault against the Borg Queen's Octahedron in the space around the Unicomplex. Although the ship is destroyed in the attack, D'Vak and most of his crew are later recovered in their escape pods.
- The Houston is likely named after the largest city in the state of Texas, which is also the 4th-largest city in the United States. It may also be named for the USS Houston, an American heavy cruiser destroyed in the Battle of Sunda Strait during World War II. The ship was heavily engaged by superior Japanese warships and went down fighting.
U.S.S. Barrett (Exchange) • U.S.S. Carnegie (Bank) • U.S.S. Chapar (Mail) • U.S.S. Borland • U.S.S. Felczer • U.S.S. Forrest • U.S.S. Hendrickson • U.S.S. Houston • U.S.S. McDonough • U.S.S. Montgomery Scott • U.S.S. Planck • U.S.S. Samoa • U.S.S. Satie • U.S.S. T'Kumbra • U.S.S. Tomlinson • U.S.S. Victory
I.K.S. Chang • I.K.S. ChoS • I.K.S. ChuQun (Bank) • I.K.S. Jorn • I.K.S. Marr • I.K.S. M'Wur • I.K.S. Q'thoq • I.K.S. Ramjep (Mail) • I.K.S. Taral • I.K.S. T'Nek • I.K.S. Wek (Exchange)